Does 5-FLUOROURACIL Cause Leukopenia? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Leukopenia have been filed in association with 5-FLUOROURACIL. This represents 1.8% of all adverse event reports for 5-FLUOROURACIL.
10
Reports of Leukopenia with 5-FLUOROURACIL
1.8%
of all 5-FLUOROURACIL reports
2
Deaths
4
Hospitalizations
How Dangerous Is Leukopenia From 5-FLUOROURACIL?
Of the 10 reports, 2 (20.0%) resulted in death, 4 (40.0%) required hospitalization.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for 5-FLUOROURACIL. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does 5-FLUOROURACIL Cause?
Breast cancer (137)
Neoplasm progression (63)
Death (37)
Nausea (35)
Neutropenia (33)
Vomiting (32)
Diarrhoea (29)
Musculoskeletal disorder (25)
Pyrexia (24)
Toxicity to various agents (20)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which 5-FLUOROURACIL Alternatives Have Lower Leukopenia Risk?
5-FLUOROURACIL vs 5-FU
5-FLUOROURACIL vs 6-ACETYLMORPHINE
5-FLUOROURACIL vs ABACAVIR
5-FLUOROURACIL vs ABACAVIR\DOLUTEGRAVIR\LAMIVUDINE
5-FLUOROURACIL vs ABACAVIR\LAMIVUDINE