Does 5-FU Cause Diarrhoea? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Diarrhoea have been filed in association with 5-FU. This represents 13.2% of all adverse event reports for 5-FU.
21
Reports of Diarrhoea with 5-FU
13.2%
of all 5-FU reports
2
Deaths
16
Hospitalizations
How Dangerous Is Diarrhoea From 5-FU?
Of the 21 reports, 2 (9.5%) resulted in death, 16 (76.2%) required hospitalization.
Is Diarrhoea Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for 5-FU. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does 5-FU Cause?
Disease progression (14)
Nausea (13)
Stomatitis (12)
Vomiting (12)
Dehydration (11)
Neutropenia (11)
Fatigue (9)
Hypertension (9)
Mucosal inflammation (9)
Pneumonia (9)
What Other Drugs Cause Diarrhoea?
LENALIDOMIDE (27,576)
APREMILAST (23,752)
ADALIMUMAB (18,120)
METHOTREXATE (12,557)
TREPROSTINIL (11,335)
CAPECITABINE (9,277)
NINTEDANIB (9,103)
ETANERCEPT (8,856)
CABOZANTINIB S-MALATE (8,282)
RITUXIMAB (8,113)
Which 5-FU Alternatives Have Lower Diarrhoea Risk?
5-FU vs 6-ACETYLMORPHINE
5-FU vs ABACAVIR
5-FU vs ABACAVIR\DOLUTEGRAVIR\LAMIVUDINE
5-FU vs ABACAVIR\LAMIVUDINE
5-FU vs ABACAVIR\LAMIVUDINE\ZIDOVUDINE