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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

ACETAMINOPHEN\PHENYLEPHRINE: 99 Adverse Event Reports & Safety Profile

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99
Total FAERS Reports
33 (33.3%)
Deaths Reported
36
Hospitalizations
99
As Primary/Secondary Suspect
27
Life-Threatening
26
Disabilities

Active Ingredient: ACETAMINOPHEN\PHENYLEPHRINE HYDROCHLORIDE ·

First Report: 2011 · Latest Report: 20241213

What Are the Most Common ACETAMINOPHEN\PHENYLEPHRINE Side Effects?

#1 Most Reported
Insomnia
26 reports (26.3%)
#2 Most Reported
Nausea
25 reports (25.3%)
#3 Most Reported
Joint swelling
24 reports (24.2%)

All ACETAMINOPHEN\PHENYLEPHRINE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Insomnia 26 26.3% 13 14
Nausea 25 25.3% 16 17
Joint swelling 24 24.2% 16 17
Headache 23 23.2% 15 17
Mobility decreased 21 21.2% 16 13
Hypersensitivity 20 20.2% 16 17
Hypertension 20 20.2% 17 17
Pemphigus 20 20.2% 13 14
Abdominal discomfort 19 19.2% 15 15
Arthralgia 19 19.2% 15 15
Confusional state 19 19.2% 16 14
Dyspnoea 19 19.2% 14 14
General physical health deterioration 19 19.2% 18 13
Glossodynia 19 19.2% 16 15
Hand deformity 19 19.2% 16 15
Hepatic enzyme increased 19 19.2% 16 15
Infusion related reaction 19 19.2% 14 16
Pyrexia 19 19.2% 11 15
Dyspepsia 18 18.2% 10 11
Fatigue 18 18.2% 15 15

Who Reports ACETAMINOPHEN\PHENYLEPHRINE Side Effects? Age & Gender Data

Gender: 90.8% female, 9.2% male. Average age: 42.0 years. Most reports from: CA. View detailed demographics →

Is ACETAMINOPHEN\PHENYLEPHRINE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2011 1 0 0
2013 3 3 0
2014 2 0 1
2015 7 0 2
2016 3 0 0
2017 2 0 1
2018 4 0 0
2019 2 0 0
2020 1 0 0
2022 2 0 1
2023 1 0 0
2024 4 0 1

View full timeline →

What Is ACETAMINOPHEN\PHENYLEPHRINE Used For?

IndicationReports
Product used for unknown indication 30
Rheumatoid arthritis 23
Pain 8
Nasal congestion 5
Off label use 5
Sinus congestion 5

Official FDA Label for ACETAMINOPHEN\PHENYLEPHRINE

Official prescribing information from the FDA-approved drug label.