ACTONEL: 153 Adverse Event Reports & Safety Profile
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153
Total FAERS Reports
6 (3.9%)
Deaths Reported
98
Hospitalizations
153
As Primary/Secondary Suspect
3
Life-Threatening
33
Disabilities
First Report: 1997 · Latest Report: 20140605
What Are the Most Common ACTONEL Side Effects?
#1 Most Reported
Femur fracture
69 reports (45.1%)
#2 Most Reported
Low turnover osteopathy
45 reports (29.4%)
#3 Most Reported
Fall
43 reports (28.1%)
All ACTONEL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Femur fracture | 69 | 45.1% | 1 | 61 |
| Low turnover osteopathy | 45 | 29.4% | 0 | 40 |
| Fall | 43 | 28.1% | 0 | 40 |
| Pain in extremity | 33 | 21.6% | 0 | 27 |
| Arthralgia | 31 | 20.3% | 0 | 25 |
| Osteoarthritis | 29 | 19.0% | 0 | 27 |
| Stress fracture | 28 | 18.3% | 0 | 23 |
| Intramedullary rod insertion | 25 | 16.3% | 0 | 25 |
| Hypertension | 20 | 13.1% | 0 | 19 |
| Pain | 18 | 11.8% | 0 | 16 |
| Fracture displacement | 17 | 11.1% | 0 | 17 |
| Pathological fracture | 17 | 11.1% | 0 | 15 |
| Bone disorder | 16 | 10.5% | 0 | 12 |
| Gastrooesophageal reflux disease | 15 | 9.8% | 0 | 12 |
| Arthritis | 14 | 9.2% | 0 | 13 |
| Fracture nonunion | 14 | 9.2% | 0 | 13 |
| Atypical femur fracture | 13 | 8.5% | 0 | 6 |
| Back pain | 13 | 8.5% | 0 | 11 |
| Depression | 13 | 8.5% | 0 | 11 |
| Anaemia | 12 | 7.8% | 0 | 12 |
Who Reports ACTONEL Side Effects? Age & Gender Data
Average age: 69.1 years. Most reports from: US. View detailed demographics →
Is ACTONEL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 3 | 0 | 3 |
| 2001 | 5 | 0 | 5 |
| 2002 | 6 | 0 | 4 |
| 2003 | 3 | 0 | 3 |
| 2004 | 1 | 0 | 0 |
| 2005 | 3 | 0 | 3 |
| 2006 | 6 | 0 | 5 |
| 2007 | 7 | 0 | 4 |
| 2008 | 6 | 0 | 5 |
| 2009 | 12 | 0 | 11 |
| 2010 | 10 | 1 | 7 |
| 2011 | 11 | 1 | 10 |
| 2012 | 9 | 0 | 8 |
| 2013 | 15 | 0 | 8 |
| 2014 | 12 | 1 | 7 |
What Is ACTONEL Used For?
| Indication | Reports |
|---|---|
| Osteoporosis | 84 |
| Osteopenia | 30 |
| Osteoporosis prophylaxis | 11 |
| Product used for unknown indication | 6 |
ACTONEL vs Alternatives: Which Is Safer?
ACTONEL vs ACYCLOVIR
ACTONEL vs AD26.COV2.S
ACTONEL vs ADAGRASIB
ACTONEL vs ADALIMUMAB
ACTONEL vs ADALIMUMAB-AACF
ACTONEL vs ADALIMUMAB-AATY
ACTONEL vs ADALIMUMAB-ADAZ
ACTONEL vs ADALIMUMAB-ADBM
ACTONEL vs ADALIMUMAB-AFZB
ACTONEL vs ADALIMUMAB-ATTO
Official FDA Label for ACTONEL
Official prescribing information from the FDA-approved drug label.