Does AFATINIB Cause Enterocolitis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Enterocolitis have been filed in association with AFATINIB (Gilotrif). This represents 0.2% of all adverse event reports for AFATINIB.
12
Reports of Enterocolitis with AFATINIB
0.2%
of all AFATINIB reports
1
Deaths
10
Hospitalizations
How Dangerous Is Enterocolitis From AFATINIB?
Of the 12 reports, 1 (8.3%) resulted in death, 10 (83.3%) required hospitalization, and 1 (8.3%) were considered life-threatening.
Is Enterocolitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Enterocolitis?
NIVOLUMAB (471)
IPILIMUMAB (321)
CAPECITABINE (291)
OXALIPLATIN (227)
METHOTREXATE (191)
PEMBROLIZUMAB (180)
RITUXIMAB (174)
DEXAMETHASONE (162)
BEVACIZUMAB (161)
CARBOPLATIN (160)
Which AFATINIB Alternatives Have Lower Enterocolitis Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE