Does AFATINIB Cause Hyperuricaemia? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Hyperuricaemia have been filed in association with AFATINIB (Gilotrif). This represents 0.1% of all adverse event reports for AFATINIB.
5
Reports of Hyperuricaemia with AFATINIB
0.1%
of all AFATINIB reports
1
Deaths
4
Hospitalizations
How Dangerous Is Hyperuricaemia From AFATINIB?
Of the 5 reports, 1 (20.0%) resulted in death, 4 (80.0%) required hospitalization, and 2 (40.0%) were considered life-threatening.
Is Hyperuricaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Hyperuricaemia?
RITUXIMAB (130)
PREDNISONE (118)
RIBAVIRIN (116)
TACROLIMUS (116)
VENETOCLAX (115)
FUROSEMIDE (100)
ALLOPURINOL (94)
RUXOLITINIB (92)
CYCLOPHOSPHAMIDE (91)
DEXAMETHASONE (87)
Which AFATINIB Alternatives Have Lower Hyperuricaemia Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE