Does AFATINIB Cause Keratitis? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Keratitis have been filed in association with AFATINIB (Gilotrif). This represents 0.2% of all adverse event reports for AFATINIB.
10
Reports of Keratitis with AFATINIB
0.2%
of all AFATINIB reports
2
Deaths
3
Hospitalizations
How Dangerous Is Keratitis From AFATINIB?
Of the 10 reports, 2 (20.0%) resulted in death, 3 (30.0%) required hospitalization.
Is Keratitis Listed in the Official Label?
Yes, Keratitis is listed as a known adverse reaction in the official FDA drug label for AFATINIB.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Keratitis?
DUPILUMAB (257)
METHOTREXATE (123)
ADALIMUMAB (96)
PREDNISOLONE (84)
ETANERCEPT (82)
ABATACEPT (72)
BELANTAMAB MAFODOTIN (66)
CYCLOSPORINE (54)
METHYLPREDNISOLONE (53)
TOCILIZUMAB (52)
Which AFATINIB Alternatives Have Lower Keratitis Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE