Does ALTEPLASE Cause Cardiac tamponade? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Cardiac tamponade have been filed in association with ALTEPLASE (Activase). This represents 0.3% of all adverse event reports for ALTEPLASE.
33
Reports of Cardiac tamponade with ALTEPLASE
0.3%
of all ALTEPLASE reports
21
Deaths
5
Hospitalizations
How Dangerous Is Cardiac tamponade From ALTEPLASE?
Of the 33 reports, 21 (63.6%) resulted in death, 5 (15.2%) required hospitalization, and 4 (12.1%) were considered life-threatening.
Is Cardiac tamponade Listed in the Official Label?
Yes, Cardiac tamponade is listed as a known adverse reaction in the official FDA drug label for ALTEPLASE.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Cardiac tamponade?
DABIGATRAN ETEXILATE (506)
ASPIRIN (208)
RIVAROXABAN (193)
APIXABAN (179)
HEPARIN (127)
WARFARIN (127)
NIVOLUMAB (124)
PEMBROLIZUMAB (122)
CLOPIDOGREL BISULFATE (116)
METHOTREXATE (86)
Which ALTEPLASE Alternatives Have Lower Cardiac tamponade Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE