Does ALTEPLASE Cause Cerebral ischaemia? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Cerebral ischaemia have been filed in association with ALTEPLASE (Activase). This represents 0.4% of all adverse event reports for ALTEPLASE.
51
Reports of Cerebral ischaemia with ALTEPLASE
0.4%
of all ALTEPLASE reports
16
Deaths
17
Hospitalizations
How Dangerous Is Cerebral ischaemia From ALTEPLASE?
Of the 51 reports, 16 (31.4%) resulted in death, 17 (33.3%) required hospitalization, and 5 (9.8%) were considered life-threatening.
Is Cerebral ischaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Cerebral ischaemia?
RIVAROXABAN (181)
ASPIRIN (121)
BEVACIZUMAB (102)
APIXABAN (92)
METHOTREXATE (82)
ADALIMUMAB (74)
DABIGATRAN ETEXILATE (64)
METFORMIN (62)
PREDNISONE (59)
RITUXIMAB (59)
Which ALTEPLASE Alternatives Have Lower Cerebral ischaemia Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE