Does ALTEPLASE Cause Disseminated intravascular coagulation? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Disseminated intravascular coagulation have been filed in association with ALTEPLASE (Activase). This represents 0.1% of all adverse event reports for ALTEPLASE.
16
Reports of Disseminated intravascular coagulation with ALTEPLASE
0.1%
of all ALTEPLASE reports
9
Deaths
4
Hospitalizations
How Dangerous Is Disseminated intravascular coagulation From ALTEPLASE?
Of the 16 reports, 9 (56.3%) resulted in death, 4 (25.0%) required hospitalization, and 3 (18.8%) were considered life-threatening.
Is Disseminated intravascular coagulation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Disseminated intravascular coagulation?
PREDNISOLONE (362)
METHOTREXATE (347)
DEXAMETHASONE (323)
METHYLPREDNISOLONE (307)
NIVOLUMAB (305)
CYCLOPHOSPHAMIDE (286)
TACROLIMUS (278)
PREDNISONE (277)
VINCRISTINE (245)
OXALIPLATIN (231)
Which ALTEPLASE Alternatives Have Lower Disseminated intravascular coagulation Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE