Does ALTEPLASE Cause Ecchymosis? 48 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 48 reports of Ecchymosis have been filed in association with ALTEPLASE (Activase). This represents 0.4% of all adverse event reports for ALTEPLASE.
48
Reports of Ecchymosis with ALTEPLASE
0.4%
of all ALTEPLASE reports
3
Deaths
14
Hospitalizations
How Dangerous Is Ecchymosis From ALTEPLASE?
Of the 48 reports, 3 (6.3%) resulted in death, 14 (29.2%) required hospitalization, and 1 (2.1%) were considered life-threatening.
Is Ecchymosis Listed in the Official Label?
Yes, Ecchymosis is listed as a known adverse reaction in the official FDA drug label for ALTEPLASE.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Ecchymosis?
RIVAROXABAN (398)
ASPIRIN (344)
WARFARIN (248)
CLOPIDOGREL BISULFATE (205)
IBRUTINIB (189)
APIXABAN (154)
METHOTREXATE (131)
PREDNISONE (118)
TOCILIZUMAB (92)
DABIGATRAN ETEXILATE (79)
Which ALTEPLASE Alternatives Have Lower Ecchymosis Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE