Does ALTEPLASE Cause Epistaxis? 97 Reports in FDA Database

Q: Does ALTEPLASE cause Epistaxis?

97 reports of Epistaxis have been filed with the FDA for ALTEPLASE, representing 0.8% of all ALTEPLASE adverse event reports.

Q: How dangerous is Epistaxis from ALTEPLASE?

Of 97 reports, 18 (18.6%) resulted in death and 23 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 97 reports of Epistaxis have been filed in association with ALTEPLASE (Activase). This represents 0.8% of all adverse event reports for ALTEPLASE.

Reports of Epistaxis with ALTEPLASE

0.8%

of all ALTEPLASE reports

Deaths

Hospitalizations

How Dangerous Is Epistaxis From ALTEPLASE?

Of the 97 reports, 18 (18.6%) resulted in death, 23 (23.7%) required hospitalization, and 10 (10.3%) were considered life-threatening.

Is Epistaxis Listed in the Official Label?

Yes, Epistaxis is listed as a known adverse reaction in the official FDA drug label for ALTEPLASE.

What Other Side Effects Does ALTEPLASE Cause?

No adverse event (2,456) Off label use (1,752) Gingival bleeding (1,018) Cerebral haemorrhage (819) Death (818) Haemorrhage intracranial (615) Angioedema (603) Haemorrhage (536) Drug ineffective (524) Haemorrhagic transformation stroke (496)

What Other Drugs Cause Epistaxis?

RIVAROXABAN (5,629) ASPIRIN (3,214) APIXABAN (2,831) FLUTICASONE (1,745) TREPROSTINIL (1,726) CLOPIDOGREL BISULFATE (1,560) BEVACIZUMAB (1,542) WARFARIN (1,498) PALBOCICLIB (1,280) ADALIMUMAB (1,243)

Which ALTEPLASE Alternatives Have Lower Epistaxis Risk?

ALTEPLASE vs ALTERNARIA ALTERNATA ALTEPLASE vs ALTHIAZIDE ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE ALTEPLASE vs ALUMINUM ALTEPLASE vs ALUMINUM HYDROXIDE

ALTEPLASE Full Profile All Epistaxis Reports All Drugs Causing Epistaxis ALTEPLASE Demographics