Does ALTEPLASE Cause Haematemesis? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Haematemesis have been filed in association with ALTEPLASE (Activase). This represents 0.5% of all adverse event reports for ALTEPLASE.
58
Reports of Haematemesis with ALTEPLASE
0.5%
of all ALTEPLASE reports
13
Deaths
21
Hospitalizations
How Dangerous Is Haematemesis From ALTEPLASE?
Of the 58 reports, 13 (22.4%) resulted in death, 21 (36.2%) required hospitalization, and 8 (13.8%) were considered life-threatening.
Is Haematemesis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Haematemesis?
ASPIRIN (1,538)
RIVAROXABAN (1,085)
CLOPIDOGREL BISULFATE (954)
IBUPROFEN (836)
APIXABAN (650)
ADALIMUMAB (563)
ACETAMINOPHEN (454)
WARFARIN (426)
SERTRALINE (412)
ENOXAPARIN (404)
Which ALTEPLASE Alternatives Have Lower Haematemesis Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE