Does ALTEPLASE Cause Intracranial pressure increased? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Intracranial pressure increased have been filed in association with ALTEPLASE (Activase). This represents 0.2% of all adverse event reports for ALTEPLASE.
23
Reports of Intracranial pressure increased with ALTEPLASE
0.2%
of all ALTEPLASE reports
15
Deaths
5
Hospitalizations
How Dangerous Is Intracranial pressure increased From ALTEPLASE?
Of the 23 reports, 15 (65.2%) resulted in death, 5 (21.7%) required hospitalization, and 1 (4.3%) were considered life-threatening.
Is Intracranial pressure increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALTEPLASE. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Intracranial pressure increased?
LEVONORGESTREL (195)
SOMATROPIN (150)
METHOTREXATE (140)
PREDNISONE (127)
ACETAMINOPHEN (123)
TACROLIMUS (104)
ADALIMUMAB (99)
DOXYCYCLINE (94)
CYCLOSPORINE (91)
MYCOPHENOLATE MOFETIL (80)
Which ALTEPLASE Alternatives Have Lower Intracranial pressure increased Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE