AMBROXOL: 906 Adverse Event Reports & Safety Profile
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906
Total FAERS Reports
55 (6.1%)
Deaths Reported
441
Hospitalizations
906
As Primary/Secondary Suspect
87
Life-Threatening
8
Disabilities
Active Ingredient: AMBROXOL HYDROCHLORIDE ·
First Report: 19940311 · Latest Report: 20250731
What Are the Most Common AMBROXOL Side Effects?
#1 Most Reported
Dyspnoea
169 reports (18.7%)
#2 Most Reported
Drug ineffective
149 reports (16.4%)
#3 Most Reported
Cough
141 reports (15.6%)
All AMBROXOL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Dyspnoea | 169 | 18.7% | 0 | 55 |
| Drug ineffective | 149 | 16.5% | 1 | 95 |
| Cough | 141 | 15.6% | 0 | 27 |
| Off label use | 138 | 15.2% | 2 | 120 |
| Chest discomfort | 134 | 14.8% | 0 | 21 |
| Nasopharyngitis | 128 | 14.1% | 0 | 10 |
| Atrial fibrillation | 125 | 13.8% | 0 | 7 |
| Dyspnoea exertional | 122 | 13.5% | 0 | 12 |
| Dysphonia | 121 | 13.4% | 0 | 10 |
| Wheezing | 121 | 13.4% | 0 | 7 |
| Obstructive airways disorder | 113 | 12.5% | 0 | 1 |
| Eosinophilia | 111 | 12.3% | 0 | 0 |
| Myoglobin blood increased | 111 | 12.3% | 0 | 0 |
| Brain natriuretic peptide increased | 110 | 12.1% | 0 | 0 |
| Coronary artery disease | 110 | 12.1% | 0 | 0 |
| Fractional exhaled nitric oxide increased | 110 | 12.1% | 0 | 0 |
| Muscle spasms | 110 | 12.1% | 0 | 0 |
| Macular degeneration | 109 | 12.0% | 0 | 79 |
| Nausea | 109 | 12.0% | 1 | 103 |
| Cardiac disorder | 107 | 11.8% | 0 | 0 |
Who Reports AMBROXOL Side Effects? Age & Gender Data
Gender: 53.0% female, 47.0% male. Average age: 57.8 years. Most reports from: DE. View detailed demographics →
Is AMBROXOL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 0 |
| 2005 | 10 | 1 | 10 |
| 2006 | 2 | 0 | 0 |
| 2010 | 1 | 0 | 1 |
| 2011 | 8 | 0 | 8 |
| 2012 | 2 | 0 | 2 |
| 2013 | 7 | 3 | 5 |
| 2014 | 16 | 1 | 7 |
| 2015 | 57 | 1 | 50 |
| 2016 | 44 | 4 | 30 |
| 2017 | 47 | 2 | 14 |
| 2018 | 156 | 1 | 30 |
| 2019 | 35 | 10 | 13 |
| 2020 | 57 | 3 | 13 |
| 2021 | 34 | 1 | 18 |
| 2022 | 13 | 1 | 5 |
| 2023 | 17 | 1 | 7 |
| 2024 | 38 | 0 | 23 |
| 2025 | 8 | 0 | 3 |
What Is AMBROXOL Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 476 |
| Productive cough | 29 |
| Pneumonia | 26 |
| Cough | 25 |
| Sputum abnormal | 23 |
| Pain | 22 |
| Asthma | 20 |
| Chronic obstructive pulmonary disease | 17 |
| Bronchitis | 16 |
| Arthralgia | 13 |
AMBROXOL vs Alternatives: Which Is Safer?
AMBROXOL vs AMDINOCILLIN PIVOXIL
AMBROXOL vs AMG-510
AMBROXOL vs AMIFAMPRIDINE
AMBROXOL vs AMIFOSTINE
AMBROXOL vs AMIKACIN
AMBROXOL vs AMILORIDE
AMBROXOL vs AMILORIDE\HYDROCHLOROTHIAZIDE
AMBROXOL vs AMINO ACIDS
AMBROXOL vs AMINO ACIDS, SOURCE UNSPECIFIED
AMBROXOL vs AMINO ACIDS\ANHYDROUS DEXTROSE\CALCIUM\MAGNESIUM HEPTAHYDRATE\POTASSIUM\SODIUM\SODIUM GLYCEROPHOSPHATE ANHYDROUS\SOYBEAN OIL
Official FDA Label for AMBROXOL
Official prescribing information from the FDA-approved drug label.