Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

AMITRIPTYLINE\PERPHENAZINE: 257 Adverse Event Reports & Safety Profile

Wake Up Pain-Free — Sleep Like Never Before

Derila Ergo Pillow: ergonomic design, cooling tech. 75% OFF today.

Shop Now — 75% Off
257
Total FAERS Reports
7 (2.7%)
Deaths Reported
151
Hospitalizations
257
As Primary/Secondary Suspect
52
Life-Threatening
8
Disabilities

Active Ingredient: AMITRIPTYLINE HYDROCHLORIDE\PERPHENAZINE ·

First Report: 1973 · Latest Report: 20231117

What Are the Most Common AMITRIPTYLINE\PERPHENAZINE Side Effects?

#1 Most Reported
Pain
126 reports (49.0%)
#2 Most Reported
Mobility decreased
120 reports (46.7%)
#3 Most Reported
Balance disorder
99 reports (38.5%)

All AMITRIPTYLINE\PERPHENAZINE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Pain 126 49.0% 0 88
Mobility decreased 120 46.7% 0 94
Balance disorder 99 38.5% 0 93
Fall 98 38.1% 0 94
Cognitive disorder 97 37.7% 0 94
Constipation 97 37.7% 0 94
Blood calcium decreased 96 37.4% 0 93
Creatinine renal clearance decreased 96 37.4% 0 93
Depressed level of consciousness 96 37.4% 0 93
Hypotension 96 37.4% 0 93
Orthostatic hypotension 96 37.4% 0 93
Sedation 96 37.4% 0 93
Toxicity to various agents 96 37.4% 0 92
Sedation complication 89 34.6% 0 89
Off label use 60 23.4% 0 30
Drug interaction 59 23.0% 0 36
Drug ineffective 49 19.1% 0 0
Dyspnoea 47 18.3% 0 35
Drug abuse 46 17.9% 0 45
Product use in unapproved indication 37 14.4% 0 30

Who Reports AMITRIPTYLINE\PERPHENAZINE Side Effects? Age & Gender Data

Gender: 96.4% female, 3.6% male. Average age: 72.3 years. Most reports from: CA. View detailed demographics →

Is AMITRIPTYLINE\PERPHENAZINE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2011 6 0 6
2013 2 0 1
2014 1 0 1
2015 3 0 1
2016 4 0 0
2017 3 0 3
2018 7 3 3
2019 8 0 5
2020 9 0 7
2021 8 0 8
2022 6 0 0
2023 2 0 2

View full timeline →

What Is AMITRIPTYLINE\PERPHENAZINE Used For?

IndicationReports
Product used for unknown indication 80
Insomnia 77
Constipation 33
Arthritis 32
Coronary artery disease 32
Dementia 32
Duodenal ulcer 32
Fibromyalgia 32
Hypertension 32
Rheumatoid arthritis 31

AMITRIPTYLINE\PERPHENAZINE vs Alternatives: Which Is Safer?

AMITRIPTYLINE\PERPHENAZINE vs AMIVANTAMAB AMITRIPTYLINE\PERPHENAZINE vs AMIVANTAMAB-VMJW AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE BESILATE AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\ATORVASTATIN AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\BENAZEPRIL AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\HYDROCHLOROTHIAZIDE\VALSARTAN AMITRIPTYLINE\PERPHENAZINE vs AMLODIPINE\INDAPAMIDE\PERINDOPRIL

Official FDA Label for AMITRIPTYLINE\PERPHENAZINE

Official prescribing information from the FDA-approved drug label.