Does AMPHOTERICIN B Cause Brain herniation? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Brain herniation have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.3% of all adverse event reports for AMPHOTERICIN B.
32
Reports of Brain herniation with AMPHOTERICIN B
0.3%
of all AMPHOTERICIN B reports
29
Deaths
28
Hospitalizations
How Dangerous Is Brain herniation From AMPHOTERICIN B?
Of the 32 reports, 29 (90.6%) resulted in death, 28 (87.5%) required hospitalization, and 4 (12.5%) were considered life-threatening.
Is Brain herniation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Brain herniation?
PREDNISONE (107)
TACROLIMUS (106)
ASPIRIN (101)
RIVAROXABAN (95)
APIXABAN (89)
CLOPIDOGREL BISULFATE (87)
ALTEPLASE (83)
HEPARIN (69)
MYCOPHENOLATE MOFETIL (64)
ACETAMINOPHEN (63)
Which AMPHOTERICIN B Alternatives Have Lower Brain herniation Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA