Does AMPHOTERICIN B Cause Exophthalmos? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Exophthalmos have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.1% of all adverse event reports for AMPHOTERICIN B.
14
Reports of Exophthalmos with AMPHOTERICIN B
0.1%
of all AMPHOTERICIN B reports
7
Deaths
9
Hospitalizations
How Dangerous Is Exophthalmos From AMPHOTERICIN B?
Of the 14 reports, 7 (50.0%) resulted in death, 9 (64.3%) required hospitalization, and 3 (21.4%) were considered life-threatening.
Is Exophthalmos Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Exophthalmos?
TEPROTUMUMAB-TRBW (124)
LEVOTHYROXINE (95)
PREDNISONE (53)
METHOTREXATE (44)
METHYLPREDNISOLONE (42)
ALEMTUZUMAB (33)
RITUXIMAB (31)
ZOLEDRONIC ACID (31)
SERTRALINE (27)
CYPROTERONE (25)
Which AMPHOTERICIN B Alternatives Have Lower Exophthalmos Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA