Does AMPHOTERICIN B Cause Histoplasmosis? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Histoplasmosis have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.2% of all adverse event reports for AMPHOTERICIN B.
24
Reports of Histoplasmosis with AMPHOTERICIN B
0.2%
of all AMPHOTERICIN B reports
4
Deaths
11
Hospitalizations
How Dangerous Is Histoplasmosis From AMPHOTERICIN B?
Of the 24 reports, 4 (16.7%) resulted in death, 11 (45.8%) required hospitalization, and 2 (8.3%) were considered life-threatening.
Is Histoplasmosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Histoplasmosis?
PREDNISONE (276)
TACROLIMUS (196)
MYCOPHENOLATE MOFETIL (192)
INFLIXIMAB (178)
ADALIMUMAB (156)
METHOTREXATE (127)
PREDNISOLONE (81)
MYCOPHENOLIC ACID (74)
AZATHIOPRINE (73)
ETANERCEPT (47)
Which AMPHOTERICIN B Alternatives Have Lower Histoplasmosis Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA