Does AMPHOTERICIN B Cause Mucormycosis? 232 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 232 reports of Mucormycosis have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 2.2% of all adverse event reports for AMPHOTERICIN B.
232
Reports of Mucormycosis with AMPHOTERICIN B
2.2%
of all AMPHOTERICIN B reports
132
Deaths
137
Hospitalizations
How Dangerous Is Mucormycosis From AMPHOTERICIN B?
Of the 232 reports, 132 (56.9%) resulted in death, 137 (59.1%) required hospitalization, and 62 (26.7%) were considered life-threatening.
Is Mucormycosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 232 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Mucormycosis?
TACROLIMUS (648)
MYCOPHENOLATE MOFETIL (468)
PREDNISONE (445)
DEXAMETHASONE (395)
METHYLPREDNISOLONE (387)
PREDNISOLONE (294)
CYCLOPHOSPHAMIDE (238)
METHOTREXATE (231)
VORICONAZOLE (216)
CYTARABINE (207)
Which AMPHOTERICIN B Alternatives Have Lower Mucormycosis Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA