Does AMPHOTERICIN B Cause Neutropenia? 233 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 233 reports of Neutropenia have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 2.2% of all adverse event reports for AMPHOTERICIN B.
233
Reports of Neutropenia with AMPHOTERICIN B
2.2%
of all AMPHOTERICIN B reports
112
Deaths
112
Hospitalizations
How Dangerous Is Neutropenia From AMPHOTERICIN B?
Of the 233 reports, 112 (48.1%) resulted in death, 112 (48.1%) required hospitalization, and 26 (11.2%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 233 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which AMPHOTERICIN B Alternatives Have Lower Neutropenia Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA