Does APREMILAST Cause Fluid retention? 209 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 209 reports of Fluid retention have been filed in association with APREMILAST (Otezla). This represents 0.2% of all adverse event reports for APREMILAST.
209
Reports of Fluid retention with APREMILAST
0.2%
of all APREMILAST reports
136
Deaths
144
Hospitalizations
How Dangerous Is Fluid retention From APREMILAST?
Of the 209 reports, 136 (65.1%) resulted in death, 144 (68.9%) required hospitalization, and 137 (65.6%) were considered life-threatening.
Is Fluid retention Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 209 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Fluid retention?
AMBRISENTAN (3,927)
TREPROSTINIL (3,804)
MACITENTAN (2,861)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (2,233)
SACUBITRIL\VALSARTAN (2,187)
ADALIMUMAB (1,193)
SELEXIPAG (1,044)
FUROSEMIDE (1,020)
LENALIDOMIDE (1,007)
EPOPROSTENOL (929)
Which APREMILAST Alternatives Have Lower Fluid retention Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA