Does APREMILAST Cause Leukopenia? 78 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 78 reports of Leukopenia have been filed in association with APREMILAST (Otezla). This represents 0.1% of all adverse event reports for APREMILAST.
78
Reports of Leukopenia with APREMILAST
0.1%
of all APREMILAST reports
16
Deaths
24
Hospitalizations
How Dangerous Is Leukopenia From APREMILAST?
Of the 78 reports, 16 (20.5%) resulted in death, 24 (30.8%) required hospitalization, and 35 (44.9%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 78 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which APREMILAST Alternatives Have Lower Leukopenia Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA