APROTININ for Heart valve replacement: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where APROTININ was used for Heart valve replacement.
Most Reported Side Effects for APROTININ
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Product use in unapproved indication | 88 | 71.0% | 32 | 60 |
| Off label use | 76 | 61.3% | 26 | 45 |
| Renal impairment | 28 | 22.6% | 11 | 26 |
| Blood creatinine increased | 22 | 17.7% | 2 | 18 |
| Ischaemic stroke | 14 | 11.3% | 4 | 11 |
| Acute kidney injury | 5 | 4.0% | 4 | 5 |
| Anaphylactic reaction | 5 | 4.0% | 1 | 0 |
Other Indications for APROTININ
Aortic dissection (26)
Aortic valve replacement (19)
Heart transplant (11)
Mitral valve replacement (9)
Cardiopulmonary bypass (7)
Coronary artery bypass (7)
Aortic surgery (5)
Other Drugs Used for Heart valve replacement
WARFARIN (228)
APIXABAN (80)
RIVAROXABAN (53)
CLOPIDOGREL BISULFATE (25)
ENOXAPARIN (15)
HEPARIN (15)
DABIGATRAN ETEXILATE (13)
PHENPROCOUMON (11)
ASPIRIN (10)
ACENOCOUMAROL (6)