AVANDAMET: 481 Adverse Event Reports & Safety Profile
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481
Total FAERS Reports
58 (12.1%)
Deaths Reported
394
Hospitalizations
481
As Primary/Secondary Suspect
4
Disabilities
First Report: 1999 · Latest Report: 201402
What Are the Most Common AVANDAMET Side Effects?
#1 Most Reported
Myocardial infarction
225 reports (46.8%)
#2 Most Reported
Cardiac failure congestive
149 reports (31.0%)
#3 Most Reported
Coronary artery disease
118 reports (24.5%)
All AVANDAMET Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Myocardial infarction | 225 | 46.8% | 26 | 199 |
| Cardiac failure congestive | 149 | 31.0% | 29 | 118 |
| Coronary artery disease | 118 | 24.5% | 13 | 111 |
| Cerebrovascular accident | 98 | 20.4% | 9 | 84 |
| Angina pectoris | 42 | 8.7% | 2 | 36 |
| Cardiac disorder | 42 | 8.7% | 3 | 36 |
| Myocardial ischaemia | 42 | 8.7% | 2 | 30 |
| Cardiovascular disorder | 36 | 7.5% | 1 | 32 |
| Angina unstable | 32 | 6.7% | 1 | 29 |
| Atrial fibrillation | 31 | 6.4% | 5 | 27 |
| Transient ischaemic attack | 24 | 5.0% | 1 | 23 |
| Acute coronary syndrome | 21 | 4.4% | 1 | 20 |
| Coronary artery bypass | 21 | 4.4% | 1 | 20 |
| Ischaemic cardiomyopathy | 20 | 4.2% | 5 | 19 |
| Acute myocardial infarction | 18 | 3.7% | 4 | 16 |
| Stent placement | 17 | 3.5% | 0 | 15 |
| Chest pain | 16 | 3.3% | 1 | 14 |
| Cardiac arrest | 15 | 3.1% | 11 | 11 |
| Dyspnoea | 14 | 2.9% | 2 | 11 |
| Death | 12 | 2.5% | 12 | 9 |
Who Reports AVANDAMET Side Effects? Age & Gender Data
Average age: 57.1 years. Most reports from: US. View detailed demographics →
Is AVANDAMET Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 5 | 0 | 5 |
| 2001 | 3 | 0 | 2 |
| 2002 | 11 | 1 | 10 |
| 2003 | 15 | 1 | 15 |
| 2004 | 27 | 2 | 25 |
| 2005 | 42 | 5 | 39 |
| 2006 | 45 | 9 | 38 |
| 2007 | 41 | 3 | 35 |
| 2008 | 27 | 5 | 24 |
| 2009 | 26 | 2 | 22 |
| 2010 | 34 | 3 | 29 |
| 2011 | 15 | 1 | 13 |
| 2012 | 3 | 1 | 3 |
| 2014 | 5 | 0 | 0 |
What Is AVANDAMET Used For?
| Indication | Reports |
|---|---|
| Diabetes mellitus | 392 |
| Type 2 diabetes mellitus | 72 |
| Product used for unknown indication | 6 |
AVANDAMET vs Alternatives: Which Is Safer?
AVANDAMET vs AVANDIA
AVANDAMET vs AVAPRITINIB
AVANDAMET vs AVASTIN
AVANDAMET vs AVATROMBOPAG
AVANDAMET vs AVELOX
AVANDAMET vs AVELUMAB
AVANDAMET vs AVIBACTAM
AVANDAMET vs AVIBACTAM\CEFTAZIDIME
AVANDAMET vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE\TITANIUM DIOXIDE\ZINC
AVANDAMET vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE
Official FDA Label for AVANDAMET
Official prescribing information from the FDA-approved drug label.