AVAPRITINIB for Systemic mastocytosis: Side Effects & Safety Data
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There are 3,988 adverse event reports in the FDA FAERS database where AVAPRITINIB was used for Systemic mastocytosis.
Most Reported Side Effects for AVAPRITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 1,527 | 15.1% | 3 | 120 |
| Off label use | 1,138 | 11.3% | 49 | 101 |
| Nausea | 1,033 | 10.2% | 5 | 93 |
| Diarrhoea | 886 | 8.8% | 6 | 86 |
| Swelling face | 481 | 4.8% | 0 | 37 |
| Memory impairment | 467 | 4.6% | 6 | 48 |
| Dizziness | 458 | 4.5% | 1 | 38 |
| Vomiting | 456 | 4.5% | 2 | 63 |
| Headache | 454 | 4.5% | 2 | 44 |
| Asthenia | 433 | 4.3% | 8 | 79 |
| Platelet count decreased | 428 | 4.2% | 9 | 54 |
| Peripheral swelling | 419 | 4.1% | 4 | 46 |
| Rash | 400 | 4.0% | 0 | 30 |
| Lacrimation increased | 396 | 3.9% | 1 | 24 |
| Decreased appetite | 391 | 3.9% | 6 | 44 |
Other Indications for AVAPRITINIB
Gastrointestinal stromal tumour (3,345)
Indolent systemic mastocytosis (843)
Advanced systemic mastocytosis (594)
Haematopoietic neoplasm (417)
Product used for unknown indication (279)
Mastocytoma (244)
Malignant mast cell neoplasm (167)
Brain neoplasm malignant (122)
Acute myeloid leukaemia (104)
Mastocytic leukaemia (83)
Other Drugs Used for Systemic mastocytosis
MIDOSTAURIN (270)
IMATINIB (63)
MONTELUKAST (43)
OMALIZUMAB (41)
RANITIDINE (40)
CETIRIZINE (34)
CROMOLYN (27)
KETOTIFEN (19)
CLADRIBINE (12)
DASATINIB (11)