AVASTIN: 1,667 Adverse Event Reports & Safety Profile
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1,667
Total FAERS Reports
606 (36.4%)
Deaths Reported
328
Hospitalizations
1,667
As Primary/Secondary Suspect
74
Life-Threatening
44
Disabilities
First Report: 20060131 · Latest Report: 20140626
What Are the Most Common AVASTIN Side Effects?
#1 Most Reported
Death
364 reports (21.8%)
#2 Most Reported
Disease progression
255 reports (15.3%)
#3 Most Reported
Off label use
158 reports (9.5%)
All AVASTIN Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 364 | 21.8% | 364 | 11 |
| Disease progression | 255 | 15.3% | 98 | 33 |
| Off label use | 158 | 9.5% | 45 | 21 |
| Fatigue | 78 | 4.7% | 25 | 14 |
| Nausea | 75 | 4.5% | 20 | 26 |
| Hypertension | 70 | 4.2% | 12 | 18 |
| Visual acuity reduced | 64 | 3.8% | 0 | 10 |
| Diarrhoea | 63 | 3.8% | 15 | 23 |
| Vision blurred | 54 | 3.2% | 1 | 6 |
| Drug ineffective | 52 | 3.1% | 18 | 6 |
| Headache | 51 | 3.1% | 4 | 18 |
| Pain | 46 | 2.8% | 12 | 12 |
| Vomiting | 45 | 2.7% | 12 | 18 |
| Dyspnoea | 43 | 2.6% | 8 | 17 |
| Asthenia | 42 | 2.5% | 13 | 16 |
| Neuropathy peripheral | 42 | 2.5% | 15 | 11 |
| Visual impairment | 37 | 2.2% | 0 | 6 |
| Vitreous floaters | 36 | 2.2% | 0 | 5 |
| Abdominal pain | 33 | 2.0% | 10 | 15 |
| Endophthalmitis | 33 | 2.0% | 0 | 0 |
Who Reports AVASTIN Side Effects? Age & Gender Data
Average age: 60.5 years. Most reports from: US. View detailed demographics →
Is AVASTIN Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2006 | 2 | 1 | 0 |
| 2007 | 3 | 0 | 0 |
| 2008 | 8 | 4 | 1 |
| 2009 | 13 | 6 | 8 |
| 2010 | 28 | 10 | 9 |
| 2011 | 69 | 25 | 16 |
| 2012 | 92 | 44 | 21 |
| 2013 | 326 | 110 | 107 |
| 2014 | 214 | 74 | 78 |
What Is AVASTIN Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 292 |
| Colon cancer | 113 |
| Colorectal cancer | 108 |
| Colorectal cancer metastatic | 90 |
| Ovarian cancer | 83 |
| Glioblastoma | 80 |
| Lung neoplasm malignant | 79 |
| Colon cancer metastatic | 70 |
| Age-related macular degeneration | 67 |
| Breast cancer metastatic | 61 |
AVASTIN vs Alternatives: Which Is Safer?
AVASTIN vs AVATROMBOPAG
AVASTIN vs AVELOX
AVASTIN vs AVELUMAB
AVASTIN vs AVIBACTAM
AVASTIN vs AVIBACTAM\CEFTAZIDIME
AVASTIN vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE\TITANIUM DIOXIDE\ZINC
AVASTIN vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE
AVASTIN vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE
AVASTIN vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE OR AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE
AVASTIN vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE
Official FDA Label for AVASTIN
Official prescribing information from the FDA-approved drug label.