AVIBACTAM for Infection: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where AVIBACTAM was used for Infection.
Most Reported Side Effects for AVIBACTAM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 31 | 15.9% | 11 | 7 |
| Death | 20 | 10.3% | 20 | 1 |
| Drug ineffective | 19 | 9.7% | 7 | 11 |
| Drug resistance | 15 | 7.7% | 6 | 8 |
| Diarrhoea | 13 | 6.7% | 7 | 3 |
| Cholestasis | 12 | 6.2% | 0 | 12 |
| Hepatic cytolysis | 12 | 6.2% | 0 | 12 |
| Hyperbilirubinaemia | 12 | 6.2% | 0 | 12 |
| Pyrexia | 12 | 6.2% | 9 | 3 |
| Disease progression | 11 | 5.6% | 8 | 2 |
| Renal impairment | 11 | 5.6% | 3 | 4 |
| Bacterial infection | 9 | 4.6% | 1 | 9 |
| Blood creatinine increased | 8 | 4.1% | 0 | 2 |
| Product use in unapproved indication | 8 | 4.1% | 6 | 2 |
| Septic shock | 8 | 4.1% | 5 | 5 |
Other Indications for AVIBACTAM
Pneumonia (36)
Product used for unknown indication (26)
Anti-infective therapy (23)
Antibiotic therapy (21)
Klebsiella infection (10)
Evidence based treatment (8)
Pneumonia klebsiella (8)
Pseudomonas infection (8)
Acute myeloid leukaemia (6)
Other Drugs Used for Infection
LEVOFLOXACIN (1,375)
PIPERACILLIN\TAZOBACTAM (1,333)
VANCOMYCIN (1,273)
CIPROFLOXACIN (1,214)
AMOXICILLIN (1,026)
SULFAMETHOXAZOLE\TRIMETHOPRIM (790)
LINEZOLID (771)
AMOXICILLIN\CLAVULANATE (705)
CEFTRIAXONE (673)
MEROPENEM (655)