BORTEZOMIB for Immune tolerance induction: Side Effects & Safety Data
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There are 35 adverse event reports in the FDA FAERS database where BORTEZOMIB was used for Immune tolerance induction.
Most Reported Side Effects for BORTEZOMIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Plasma cell myeloma | 6,683 | 14.0% | 1,185 | 694 |
| Off label use | 4,754 | 10.0% | 956 | 1,101 |
| Neuropathy peripheral | 4,067 | 8.5% | 226 | 488 |
| Drug ineffective | 2,730 | 5.7% | 565 | 532 |
| Diarrhoea | 2,244 | 4.7% | 296 | 944 |
| Thrombocytopenia | 2,082 | 4.4% | 391 | 716 |
| Death | 2,025 | 4.2% | 2,018 | 251 |
| Pneumonia | 2,020 | 4.2% | 519 | 1,308 |
| Fatigue | 1,757 | 3.7% | 188 | 446 |
| Neutropenia | 1,530 | 3.2% | 247 | 428 |
| Anaemia | 1,486 | 3.1% | 306 | 593 |
| Disease progression | 1,399 | 2.9% | 355 | 233 |
| Pyrexia | 1,384 | 2.9% | 204 | 854 |
| Intentional product use issue | 1,361 | 2.9% | 250 | 126 |
| Nausea | 1,318 | 2.8% | 160 | 501 |
Other Indications for BORTEZOMIB
Plasma cell myeloma (31,567)
Product used for unknown indication (6,690)
Amyloidosis (1,044)
Primary amyloidosis (905)
Plasma cell myeloma refractory (848)
Mantle cell lymphoma (630)
Plasma cell leukaemia (458)
Waldenstrom's macroglobulinaemia (425)
Chemotherapy (298)
Plasmablastic lymphoma (216)
Other Drugs Used for Immune tolerance induction
RITUXIMAB (207)
HUMAN IMMUNOGLOBULIN G (88)
ASPIRIN (62)
MYCOPHENOLATE MOFETIL (62)
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT (53)
--BLOOD-COAGULATION FACTOR VIII FUSION PROTEIN WITH IMMUNOGLOBULIN G1 , ,-BIS WITH IMMUNOGLOBULIN G1 (52)
EFMOROCTOCOG ALFA (46)
PHLEUM PRATENSE POLLEN (36)
OXALIPLATIN (33)
TACROLIMUS (33)