BOSENTAN for Systemic scleroderma: Side Effects & Safety Data
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There are 120 adverse event reports in the FDA FAERS database where BOSENTAN was used for Systemic scleroderma.
Most Reported Side Effects for BOSENTAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Dyspnoea | 2,492 | 12.7% | 501 | 1,640 |
| Death | 2,388 | 12.2% | 2,384 | 689 |
| Pneumonia | 1,064 | 5.4% | 264 | 946 |
| Fatigue | 1,025 | 5.2% | 116 | 449 |
| Headache | 962 | 4.9% | 94 | 467 |
| Hospitalisation | 915 | 4.7% | 105 | 913 |
| Malaise | 894 | 4.6% | 130 | 445 |
| Diarrhoea | 840 | 4.3% | 132 | 484 |
| Product dose omission issue | 798 | 4.1% | 18 | 174 |
| Pulmonary arterial hypertension | 778 | 4.0% | 358 | 506 |
| Nausea | 765 | 3.9% | 98 | 428 |
| Condition aggravated | 739 | 3.8% | 239 | 464 |
| Dizziness | 721 | 3.7% | 95 | 376 |
| Cough | 705 | 3.6% | 100 | 400 |
| Off label use | 659 | 3.4% | 100 | 272 |
Other Indications for BOSENTAN
Pulmonary arterial hypertension (12,387)
Product used for unknown indication (3,679)
Pulmonary hypertension (2,337)
Scleroderma associated digital ulcer (246)
Skin ulcer (211)
Heart disease congenital (65)
Connective tissue disorder (62)
Cor pulmonale chronic (60)
Raynaud's phenomenon (59)
Scleroderma (52)
Other Drugs Used for Systemic scleroderma
RITUXIMAB (554)
MYCOPHENOLATE MOFETIL (474)
TOCILIZUMAB (332)
METHOTREXATE (307)
NINTEDANIB (204)
PREDNISOLONE (156)
CYCLOPHOSPHAMIDE (142)
PREDNISONE (128)
IMATINIB (118)
SILDENAFIL (82)