BRENTUXIMAB for Diffuse large b-cell lymphoma: Side Effects & Safety Data
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There are 18 adverse event reports in the FDA FAERS database where BRENTUXIMAB was used for Diffuse large b-cell lymphoma.
Most Reported Side Effects for BRENTUXIMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 40 | 22.2% | 13 | 21 |
| Drug ineffective | 30 | 16.7% | 7 | 9 |
| Disease progression | 23 | 12.8% | 6 | 2 |
| Febrile neutropenia | 14 | 7.8% | 0 | 9 |
| Malignant neoplasm progression | 13 | 7.2% | 7 | 7 |
| Neuropathy peripheral | 10 | 5.6% | 0 | 5 |
| Product use in unapproved indication | 9 | 5.0% | 2 | 5 |
| Tubulointerstitial nephritis | 9 | 5.0% | 0 | 8 |
| Acute kidney injury | 8 | 4.4% | 1 | 8 |
| Pancytopenia | 8 | 4.4% | 1 | 6 |
| Sepsis | 8 | 4.4% | 4 | 3 |
| Vomiting | 8 | 4.4% | 1 | 5 |
| C-reactive protein increased | 7 | 3.9% | 0 | 6 |
| Covid-19 | 7 | 3.9% | 4 | 6 |
| Disease recurrence | 7 | 3.9% | 0 | 0 |
Other Indications for BRENTUXIMAB
Hodgkin's disease (61)
Cutaneous t-cell lymphoma (15)
Product used for unknown indication (13)
Chemotherapy (10)
Anaplastic large cell lymphoma t- and null-cell types (9)
Hodgkin's disease recurrent (8)
Adult t-cell lymphoma/leukaemia (6)
Non-hodgkin's lymphoma (5)
Primary mediastinal large b-cell lymphoma recurrent (5)
Other Drugs Used for Diffuse large b-cell lymphoma
RITUXIMAB (22,275)
CYCLOPHOSPHAMIDE (16,598)
DOXORUBICIN (15,213)
VINCRISTINE (14,922)
PREDNISONE (11,266)
LENALIDOMIDE (7,858)
ETOPOSIDE (4,698)
PREDNISOLONE (4,086)
CYTARABINE (3,857)
DEXAMETHASONE (3,696)