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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

BRINZOLAMIDE\TIMOLOL: 576 Adverse Event Reports & Safety Profile

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576
Total FAERS Reports
17 (3.0%)
Deaths Reported
164
Hospitalizations
576
As Primary/Secondary Suspect
6
Life-Threatening
17
Disabilities

Active Ingredient: BRINZOLAMIDE\TIMOLOL MALEATE ·

First Report: 1994 · Latest Report: 20250506

What Are the Most Common BRINZOLAMIDE\TIMOLOL Side Effects?

#1 Most Reported
Toxic epidermal necrolysis
90 reports (15.6%)
#2 Most Reported
Cataract
61 reports (10.6%)
#3 Most Reported
Off label use
57 reports (9.9%)

All BRINZOLAMIDE\TIMOLOL Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Toxic epidermal necrolysis 90 15.6% 0 90
Cataract 61 10.6% 0 2
Off label use 57 9.9% 0 52
Intraocular pressure increased 52 9.0% 0 8
Haemoglobin decreased 51 8.9% 0 51
Rash papular 46 8.0% 0 45
Rash erythematous 44 7.6% 0 44
Visual impairment 44 7.6% 0 4
Glaucoma 38 6.6% 0 4
Product use in unapproved indication 34 5.9% 0 27
Malaise 33 5.7% 1 9
Ocular hyperaemia 33 5.7% 0 2
Drug ineffective 32 5.6% 0 6
Eye pain 31 5.4% 0 1
Epidermal necrosis 28 4.9% 0 28
Blindness 26 4.5% 0 3
Visual acuity reduced 25 4.3% 0 0
Vision blurred 22 3.8% 0 2
Nikolsky's sign positive 19 3.3% 0 19
Bradycardia 18 3.1% 0 8

Who Reports BRINZOLAMIDE\TIMOLOL Side Effects? Age & Gender Data

Gender: 73.8% female, 26.2% male. Average age: 71.0 years. Most reports from: CA. View detailed demographics →

Is BRINZOLAMIDE\TIMOLOL Getting Safer? Reports by Year

YearReportsDeathsHosp.
2001 1 0 0
2010 2 0 0
2011 1 0 0
2012 4 0 1
2013 6 0 1
2014 16 0 4
2015 37 0 10
2016 25 1 7
2017 35 2 10
2018 30 2 4
2019 20 2 6
2020 18 1 3
2021 10 0 2
2022 14 1 3
2023 3 0 1
2024 5 0 1
2025 6 0 0

View full timeline →

What Is BRINZOLAMIDE\TIMOLOL Used For?

IndicationReports
Glaucoma 293
Product used for unknown indication 157
Intraocular pressure increased 43
Open angle glaucoma 21
Ocular hypertension 19

BRINZOLAMIDE\TIMOLOL vs Alternatives: Which Is Safer?

BRINZOLAMIDE\TIMOLOL vs BRIVARACETAM BRINZOLAMIDE\TIMOLOL vs BRIVUDINE BRINZOLAMIDE\TIMOLOL vs BRODALUMAB BRINZOLAMIDE\TIMOLOL vs BROLUCIZUMAB BRINZOLAMIDE\TIMOLOL vs BROLUCIZUMAB-DBLL BRINZOLAMIDE\TIMOLOL vs BROMAZEPAM BRINZOLAMIDE\TIMOLOL vs BROMFENAC BRINZOLAMIDE\TIMOLOL vs BROMHEXINE BRINZOLAMIDE\TIMOLOL vs BROMOCRIPTINE BRINZOLAMIDE\TIMOLOL vs BROTIZOLAM

Official FDA Label for BRINZOLAMIDE\TIMOLOL

Official prescribing information from the FDA-approved drug label.