Does BUPIVACAINE Cause Bradycardia? 227 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 227 reports of Bradycardia have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 2.0% of all adverse event reports for BUPIVACAINE.
227
Reports of Bradycardia with BUPIVACAINE
2.0%
of all BUPIVACAINE reports
10
Deaths
97
Hospitalizations
How Dangerous Is Bradycardia From BUPIVACAINE?
Of the 227 reports, 10 (4.4%) resulted in death, 97 (42.7%) required hospitalization, and 85 (37.4%) were considered life-threatening.
Is Bradycardia Listed in the Official Label?
Yes, Bradycardia is listed as a known adverse reaction in the official FDA drug label for BUPIVACAINE.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Bradycardia?
BISOPROLOL (2,535)
METOPROLOL (2,024)
AMLODIPINE (1,840)
AMIODARONE (1,261)
FUROSEMIDE (1,032)
ATENOLOL (942)
PROPRANOLOL (934)
DIGOXIN (896)
CARVEDILOL (861)
FINGOLIMOD (861)
Which BUPIVACAINE Alternatives Have Lower Bradycardia Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE