Does BUPIVACAINE Cause Paralysis? 77 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 77 reports of Paralysis have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 0.7% of all adverse event reports for BUPIVACAINE.
77
Reports of Paralysis with BUPIVACAINE
0.7%
of all BUPIVACAINE reports
3
Deaths
53
Hospitalizations
How Dangerous Is Paralysis From BUPIVACAINE?
Of the 77 reports, 3 (3.9%) resulted in death, 53 (68.8%) required hospitalization, and 29 (37.7%) were considered life-threatening.
Is Paralysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPIVACAINE. However, 77 reports have been filed with the FAERS database.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Paralysis?
ADALIMUMAB (275)
INTERFERON BETA-1A (181)
METHOTREXATE (181)
PREGABALIN (171)
RITUXIMAB (166)
ATORVASTATIN (160)
DIMETHYL (156)
FINGOLIMOD (145)
NATALIZUMAB (136)
ETANERCEPT (134)
Which BUPIVACAINE Alternatives Have Lower Paralysis Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE