Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

CAFFEINE vs METHYLPHENIDATE: Which Drug Is Safer?

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now

CAFFEINE vs METHYLPHENIDATE: Safety Overview

Metric CAFFEINE METHYLPHENIDATE
Total FAERS Reports 3,107 31,008
Deaths Reported 1,667 1,163
Death Rate 53.7% 3.8%
Hospitalizations 983 4,620
Average Patient Age 43.0 yrs 22.6 yrs
% Female Patients 57.2% 39.4%
FDA Approval Date Apr 12, 2000 Approved Prior to Jan 1, 1982
Manufacturer Fresenius Kabi USA, LLC Bryant Ranch Prepack
Route INTRAVENOUS ORAL
Marketing Status Prescription Prescription