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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

CHLORPROTHIXENE: 639 Adverse Event Reports & Safety Profile

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639
Total FAERS Reports
128 (20.0%)
Deaths Reported
354
Hospitalizations
639
As Primary/Secondary Suspect
153
Life-Threatening
15
Disabilities
Approved Prior to Jan 1, 1982
FDA Approved
Discontinued
Status

FDA Application: 012486 ·

First Report: 19911104 · Latest Report: 20250301

What Are the Most Common CHLORPROTHIXENE Side Effects?

#1 Most Reported
Toxicity to various agents
117 reports (18.3%)
#2 Most Reported
Drug ineffective
75 reports (11.7%)
#3 Most Reported
Intentional overdose
71 reports (11.1%)

All CHLORPROTHIXENE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Toxicity to various agents 117 18.3% 51 56
Drug ineffective 75 11.7% 0 52
Intentional overdose 71 11.1% 0 58
Intentional self-injury 67 10.5% 16 50
Suicidal ideation 66 10.3% 2 49
Suicide attempt 58 9.1% 0 36
Neuroleptic malignant syndrome 53 8.3% 7 33
Weight increased 53 8.3% 6 32
Anxiety 46 7.2% 11 33
Restlessness 45 7.0% 8 29
Fatigue 39 6.1% 0 23
Somnolence 39 6.1% 0 26
Serotonin syndrome 38 6.0% 1 34
Drug abuse 37 5.8% 10 18
Off label use 34 5.3% 6 18
Vomiting 34 5.3% 12 23
Drug interaction 33 5.2% 0 23
Nausea 33 5.2% 6 17
Hallucination 31 4.9% 7 21
Rhabdomyolysis 31 4.9% 0 24

Who Reports CHLORPROTHIXENE Side Effects? Age & Gender Data

Gender: 54.5% female, 45.5% male. Average age: 40.4 years. Most reports from: DE. View detailed demographics →

Is CHLORPROTHIXENE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2000 1 0 0
2005 1 0 1
2007 4 0 0
2008 6 0 1
2009 4 0 3
2010 2 0 0
2011 21 0 18
2012 30 20 10
2013 14 3 7
2014 15 0 6
2015 11 2 5
2016 33 2 25
2017 39 10 28
2018 49 2 25
2019 24 1 17
2020 15 0 6
2021 13 4 6
2022 9 0 1
2023 4 0 4
2024 11 0 10
2025 9 0 7

View full timeline →

What Is CHLORPROTHIXENE Used For?

IndicationReports
Product used for unknown indication 293
Schizophrenia 61
Depression 43
Mental disorder 29
Anxiety 24
Psychotic disorder 23
Psychotherapy 20
Sedation 12
Schizoaffective disorder 11
Sleep disorder 11

CHLORPROTHIXENE vs Alternatives: Which Is Safer?

CHLORPROTHIXENE vs CHLORTHALIDONE CHLORPROTHIXENE vs CHLORZOXAZONE CHLORPROTHIXENE vs CHOLECALCIFEROL CHLORPROTHIXENE vs CHOLECALCIFEROL\ERGOCALCIFEROL CHLORPROTHIXENE vs CHOLESTYRAMINE CHLORPROTHIXENE vs CHOLIC ACID CHLORPROTHIXENE vs CHONDROITIN CHLORPROTHIXENE vs CHONDROITIN \GLUCOSAMINE CHLORPROTHIXENE vs CHORIOGONADOTROPIN ALFA CHLORPROTHIXENE vs CIALIS

Official FDA Label for CHLORPROTHIXENE

Official prescribing information from the FDA-approved drug label.