CINRYZE: 141 Adverse Event Reports & Safety Profile
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141
Total FAERS Reports
1 (0.7%)
Deaths Reported
95
Hospitalizations
141
As Primary/Secondary Suspect
First Report: 200810 · Latest Report: 20140614
What Are the Most Common CINRYZE Side Effects?
#1 Most Reported
Hereditary angioedema
119 reports (84.4%)
#2 Most Reported
Inappropriate schedule of drug administration
28 reports (19.9%)
#3 Most Reported
Off label use
22 reports (15.6%)
All CINRYZE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Hereditary angioedema | 119 | 84.4% | 1 | 81 |
| Inappropriate schedule of drug administration | 28 | 19.9% | 0 | 18 |
| Angioedema | 22 | 15.6% | 0 | 12 |
| Off label use | 22 | 15.6% | 0 | 17 |
| Therapy change | 13 | 9.2% | 0 | 11 |
| Drug dose omission | 11 | 7.8% | 0 | 10 |
| Nausea | 8 | 5.7% | 0 | 5 |
| Drug ineffective | 7 | 5.0% | 0 | 5 |
| Stress | 6 | 4.3% | 0 | 5 |
| Swelling | 6 | 4.3% | 0 | 5 |
| Condition aggravated | 5 | 3.6% | 0 | 5 |
| Dizziness | 5 | 3.6% | 0 | 3 |
| Dyspnoea | 5 | 3.6% | 0 | 4 |
| Hypersensitivity | 5 | 3.6% | 0 | 4 |
| Incorrect drug administration duration | 5 | 3.6% | 0 | 2 |
| Malaise | 5 | 3.6% | 0 | 4 |
| Pharyngeal oedema | 5 | 3.6% | 0 | 1 |
| Pyrexia | 5 | 3.6% | 0 | 3 |
Who Reports CINRYZE Side Effects? Age & Gender Data
Average age: 35.2 years. Most reports from: US. View detailed demographics →
Is CINRYZE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2008 | 1 | 0 | 0 |
| 2009 | 17 | 0 | 7 |
| 2010 | 26 | 1 | 11 |
| 2011 | 24 | 0 | 24 |
| 2012 | 28 | 0 | 27 |
| 2013 | 15 | 0 | 10 |
| 2014 | 16 | 0 | 8 |
What Is CINRYZE Used For?
| Indication | Reports |
|---|---|
| Hereditary angioedema | 132 |
| Prophylaxis | 104 |
CINRYZE vs Alternatives: Which Is Safer?
CINRYZE vs CIPRO
CINRYZE vs CIPROFLOXACIN
CINRYZE vs CIPROFLOXACIN\DEXAMETHASONE
CINRYZE vs CIPROFLOXACIN\FLUOCINOLONE ACETONIDE
CINRYZE vs CISAPRIDE
CINRYZE vs CISATRACURIUM
CINRYZE vs CISPLATIN
CINRYZE vs CISPLATIN\CYTARABINE\DEXAMETHASONE
CINRYZE vs CITALOPRAM
CINRYZE vs CITALOPRAM HYDROBROMIDE
Official FDA Label for CINRYZE
Official prescribing information from the FDA-approved drug label.