CLOMETHIAZOLE: 229 Adverse Event Reports & Safety Profile
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229
Total FAERS Reports
46 (20.1%)
Deaths Reported
154
Hospitalizations
229
As Primary/Secondary Suspect
77
Life-Threatening
17
Disabilities
First Report: 19991208 · Latest Report: 20250426
What Are the Most Common CLOMETHIAZOLE Side Effects?
#1 Most Reported
Abdominal pain
29 reports (12.7%)
#2 Most Reported
Fall
27 reports (11.8%)
#3 Most Reported
Nausea
26 reports (11.4%)
All CLOMETHIAZOLE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Abdominal pain | 29 | 12.7% | 24 | 27 |
| Fall | 27 | 11.8% | 3 | 25 |
| Nausea | 26 | 11.4% | 25 | 25 |
| Abdominal distension | 25 | 10.9% | 25 | 24 |
| White blood cell count increased | 23 | 10.0% | 21 | 20 |
| Dementia | 22 | 9.6% | 21 | 20 |
| Subileus | 22 | 9.6% | 22 | 21 |
| Abdominal tenderness | 21 | 9.2% | 21 | 20 |
| Faecaloma | 21 | 9.2% | 21 | 21 |
| Gastrointestinal sounds abnormal | 21 | 9.2% | 21 | 20 |
| Ileus | 21 | 9.2% | 21 | 20 |
| Pancreatitis | 21 | 9.2% | 21 | 20 |
| Vascular encephalopathy | 21 | 9.2% | 21 | 20 |
| Intentional overdose | 20 | 8.7% | 0 | 14 |
| Bladder disorder | 18 | 7.9% | 18 | 17 |
| Intentional self-injury | 18 | 7.9% | 0 | 13 |
| General physical health deterioration | 17 | 7.4% | 5 | 14 |
| Toxic epidermal necrolysis | 17 | 7.4% | 0 | 13 |
| Toxicity to various agents | 16 | 7.0% | 1 | 13 |
| Agitation | 13 | 5.7% | 0 | 3 |
Who Reports CLOMETHIAZOLE Side Effects? Age & Gender Data
Gender: 52.7% female, 47.3% male. Average age: 66.2 years. Most reports from: DE. View detailed demographics →
Is CLOMETHIAZOLE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2005 | 8 | 0 | 8 |
| 2008 | 1 | 0 | 1 |
| 2009 | 23 | 23 | 22 |
| 2012 | 3 | 0 | 3 |
| 2013 | 4 | 0 | 4 |
| 2014 | 7 | 1 | 5 |
| 2015 | 7 | 0 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 31 | 3 | 26 |
| 2018 | 19 | 0 | 6 |
| 2019 | 11 | 3 | 7 |
| 2020 | 13 | 0 | 8 |
| 2021 | 17 | 3 | 7 |
| 2022 | 3 | 0 | 1 |
| 2023 | 3 | 0 | 1 |
| 2024 | 13 | 0 | 12 |
| 2025 | 10 | 1 | 10 |
What Is CLOMETHIAZOLE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 101 |
| Anxiety | 16 |
| Sleep disorder | 13 |
| Premedication | 12 |
| Alcohol withdrawal syndrome | 8 |
| Bipolar disorder | 8 |
| Insomnia | 7 |
| Schizophrenia | 6 |
CLOMETHIAZOLE vs Alternatives: Which Is Safer?
CLOMETHIAZOLE vs CLOMIPHENE
CLOMETHIAZOLE vs CLOMIPRAMINE
CLOMETHIAZOLE vs CLONAZEPAM
CLOMETHIAZOLE vs CLONIDINE
CLOMETHIAZOLE vs CLOPIDOGREL
CLOMETHIAZOLE vs CLOPIDOGREL BESILATE
CLOMETHIAZOLE vs CLOPIDOGREL BISULFATE
CLOMETHIAZOLE vs CLORAZEPATE
CLOMETHIAZOLE vs CLOSTRIDIUM TETANI TOXOID ANTIGEN
CLOMETHIAZOLE vs CLOTHIAPINE
Official FDA Label for CLOMETHIAZOLE
Official prescribing information from the FDA-approved drug label.