CLOZARIL: 1,250 Adverse Event Reports & Safety Profile
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1,250
Total FAERS Reports
251 (20.1%)
Deaths Reported
684
Hospitalizations
1,250
As Primary/Secondary Suspect
49
Life-Threatening
36
Disabilities
First Report: 1996 · Latest Report: 20140620
What Are the Most Common CLOZARIL Side Effects?
#1 Most Reported
White blood cell count increased
243 reports (19.4%)
#2 Most Reported
Neutrophil count increased
224 reports (17.9%)
#3 Most Reported
Death
117 reports (9.4%)
All CLOZARIL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| White blood cell count increased | 243 | 19.4% | 30 | 171 |
| Neutrophil count increased | 224 | 17.9% | 30 | 159 |
| Death | 117 | 9.4% | 117 | 13 |
| Malaise | 88 | 7.0% | 7 | 70 |
| Haemoglobin decreased | 79 | 6.3% | 9 | 40 |
| White blood cell count decreased | 65 | 5.2% | 3 | 34 |
| Schizophrenia | 61 | 4.9% | 1 | 49 |
| Pneumonia | 60 | 4.8% | 18 | 49 |
| Tachycardia | 59 | 4.7% | 2 | 29 |
| Platelet count increased | 54 | 4.3% | 12 | 35 |
| Platelet count decreased | 49 | 3.9% | 4 | 20 |
| Mental impairment | 47 | 3.8% | 1 | 36 |
| Psychotic disorder | 47 | 3.8% | 0 | 31 |
| Lower respiratory tract infection | 45 | 3.6% | 9 | 34 |
| Neutrophil count decreased | 44 | 3.5% | 0 | 24 |
| Fall | 39 | 3.1% | 8 | 34 |
| Pyrexia | 38 | 3.0% | 3 | 26 |
| Differential white blood cell count abnormal | 37 | 3.0% | 0 | 20 |
| Dyspnoea | 37 | 3.0% | 8 | 23 |
| Urinary tract infection | 37 | 3.0% | 0 | 27 |
Who Reports CLOZARIL Side Effects? Age & Gender Data
Average age: 47.6 years. Most reports from: GB. View detailed demographics →
Is CLOZARIL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 0 |
| 2002 | 2 | 0 | 1 |
| 2003 | 1 | 0 | 0 |
| 2004 | 4 | 0 | 1 |
| 2005 | 3 | 1 | 1 |
| 2006 | 1 | 1 | 1 |
| 2007 | 3 | 1 | 2 |
| 2008 | 4 | 1 | 2 |
| 2009 | 5 | 3 | 4 |
| 2010 | 10 | 1 | 4 |
| 2011 | 16 | 7 | 9 |
| 2012 | 48 | 11 | 21 |
| 2013 | 287 | 53 | 155 |
| 2014 | 337 | 81 | 183 |
What Is CLOZARIL Used For?
| Indication | Reports |
|---|---|
| Schizophrenia | 582 |
| Schizophrenia, paranoid type | 42 |
| Schizoaffective disorder | 34 |
| Psychotic disorder | 32 |
| Product used for unknown indication | 14 |
| Bipolar disorder | 7 |
| Off label use | 7 |
| Borderline personality disorder | 5 |
| Hallucination | 5 |
CLOZARIL vs Alternatives: Which Is Safer?
CLOZARIL vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZARIL vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZARIL vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZARIL vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL
CLOZARIL vs COAGULATION FACTOR VIIA RECOMBINANT HUMAN
CLOZARIL vs COBAMAMIDE
CLOZARIL vs COBICISTAT
CLOZARIL vs COBICISTAT\DARUNAVIR ETHANOLATE
CLOZARIL vs COBICISTAT\DARUNAVIR\EMTRICITABINE\TENOFOVIR ALAFENAMIDE
CLOZARIL vs COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR
Official FDA Label for CLOZARIL
Official prescribing information from the FDA-approved drug label.