Does COBIMETINIB Cause Melaena? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Melaena have been filed in association with COBIMETINIB (Cotellic). This represents 0.2% of all adverse event reports for COBIMETINIB.
6
Reports of Melaena with COBIMETINIB
0.2%
of all COBIMETINIB reports
0
Deaths
4
Hospitalizations
How Dangerous Is Melaena From COBIMETINIB?
Of the 6 reports, 4 (66.7%) required hospitalization, and 2 (33.3%) were considered life-threatening.
Is Melaena Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Melaena?
ASPIRIN (2,001)
CLOPIDOGREL BISULFATE (1,547)
RIVAROXABAN (1,405)
APIXABAN (1,156)
WARFARIN (930)
IBUPROFEN (810)
DABIGATRAN ETEXILATE (700)
DICLOFENAC (576)
NAPROXEN (291)
FUROSEMIDE (272)
Which COBIMETINIB Alternatives Have Lower Melaena Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE