Does COBIMETINIB Cause Peripheral motor neuropathy? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Peripheral motor neuropathy have been filed in association with COBIMETINIB (Cotellic). This represents 0.2% of all adverse event reports for COBIMETINIB.
9
Reports of Peripheral motor neuropathy with COBIMETINIB
0.2%
of all COBIMETINIB reports
1
Deaths
7
Hospitalizations
How Dangerous Is Peripheral motor neuropathy From COBIMETINIB?
Of the 9 reports, 1 (11.1%) resulted in death, 7 (77.8%) required hospitalization, and 6 (66.7%) were considered life-threatening.
Is Peripheral motor neuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Peripheral motor neuropathy?
VINCRISTINE (133)
CYCLOPHOSPHAMIDE (122)
DOXORUBICIN (106)
DEXAMETHASONE (104)
PACLITAXEL (94)
ETOPOSIDE (68)
METHOTREXATE (68)
CARBOPLATIN (66)
BEVACIZUMAB (64)
BRENTUXIMAB VEDOTIN (62)
Which COBIMETINIB Alternatives Have Lower Peripheral motor neuropathy Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE