Does CODEINE Cause Hepatic cirrhosis? 147 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 147 reports of Hepatic cirrhosis have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.7% of all adverse event reports for CODEINE.
147
Reports of Hepatic cirrhosis with CODEINE
0.7%
of all CODEINE reports
140
Deaths
131
Hospitalizations
How Dangerous Is Hepatic cirrhosis From CODEINE?
Of the 147 reports, 140 (95.2%) resulted in death, 131 (89.1%) required hospitalization, and 127 (86.4%) were considered life-threatening.
Is Hepatic cirrhosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 147 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Hepatic cirrhosis?
ADALIMUMAB (1,760)
METHOTREXATE (1,650)
ETANERCEPT (931)
TOCILIZUMAB (903)
RITUXIMAB (863)
INFLIXIMAB (831)
ABATACEPT (824)
HYDROXYCHLOROQUINE (807)
LEFLUNOMIDE (780)
SULFASALAZINE (760)
Which CODEINE Alternatives Have Lower Hepatic cirrhosis Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE