COLISTIMETHATE for Bronchiectasis: Side Effects & Safety Data
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There are 17 adverse event reports in the FDA FAERS database where COLISTIMETHATE was used for Bronchiectasis.
Most Reported Side Effects for COLISTIMETHATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 96 | 11.4% | 9 | 16 |
| Acute kidney injury | 91 | 10.8% | 11 | 47 |
| Condition aggravated | 68 | 8.1% | 8 | 19 |
| Drug ineffective | 48 | 5.7% | 22 | 24 |
| Septic shock | 40 | 4.7% | 28 | 19 |
| Rash maculo-papular | 37 | 4.4% | 0 | 3 |
| Death | 36 | 4.3% | 35 | 2 |
| Eosinophilia | 35 | 4.1% | 0 | 6 |
| Thrombocytopenia | 34 | 4.0% | 1 | 3 |
| Leukocytosis | 33 | 3.9% | 0 | 7 |
| Multiple organ dysfunction syndrome | 32 | 3.8% | 22 | 17 |
| Hepatic cytolysis | 30 | 3.6% | 0 | 4 |
| Renal failure | 29 | 3.4% | 7 | 15 |
| Product use issue | 27 | 3.2% | 4 | 2 |
| Hospitalisation | 26 | 3.1% | 0 | 24 |
Other Indications for COLISTIMETHATE
Cystic fibrosis (129)
Product used for unknown indication (119)
Pseudomonas infection (56)
Acinetobacter infection (52)
Bacterial infection (46)
Pneumonia (34)
Infection (31)
Klebsiella infection (30)
Antibiotic therapy (24)
Pneumonia pseudomonal (17)
Other Drugs Used for Bronchiectasis
TOBRAMYCIN (977)
AZTREONAM LYSINE (720)
DORNASE ALFA (137)
DUPILUMAB (97)
AMIKACIN (96)
FLUTICASONE\SALMETEROL (91)
TIOTROPIUM (77)
AZITHROMYCIN (70)
BUDESONIDE\FORMOTEROL (69)
FLUTICASONE FUROATE\VILANTEROL TRIFENATATE (63)