CYCLOPHOSPHAMIDE for Factor viii deficiency: Side Effects & Safety Data
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There are 22 adverse event reports in the FDA FAERS database where CYCLOPHOSPHAMIDE was used for Factor viii deficiency.
Most Reported Side Effects for CYCLOPHOSPHAMIDE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 12,578 | 9.8% | 2,788 | 3,928 |
| Febrile neutropenia | 11,318 | 8.8% | 1,348 | 7,223 |
| Drug ineffective | 8,142 | 6.3% | 2,157 | 2,184 |
| Neutropenia | 7,352 | 5.7% | 1,287 | 2,890 |
| Disease progression | 7,100 | 5.5% | 1,730 | 1,008 |
| Pyrexia | 6,126 | 4.8% | 832 | 4,228 |
| Product use in unapproved indication | 5,750 | 4.5% | 1,245 | 1,392 |
| Thrombocytopenia | 4,669 | 3.6% | 902 | 1,799 |
| Pneumonia | 4,595 | 3.6% | 1,633 | 2,604 |
| Nausea | 4,561 | 3.6% | 363 | 2,190 |
| Anaemia | 4,486 | 3.5% | 664 | 2,040 |
| Death | 4,270 | 3.3% | 4,260 | 453 |
| Sepsis | 4,041 | 3.1% | 2,077 | 1,841 |
| Myelosuppression | 3,603 | 2.8% | 209 | 1,796 |
| Diarrhoea | 3,602 | 2.8% | 566 | 1,861 |
Other Indications for CYCLOPHOSPHAMIDE
Diffuse large b-cell lymphoma (16,598)
Plasma cell myeloma (9,148)
Breast cancer (8,826)
Product used for unknown indication (8,261)
Acute lymphocytic leukaemia (5,495)
B-cell lymphoma (4,766)
Bone marrow conditioning regimen (4,485)
Non-hodgkin's lymphoma (3,805)
Chemotherapy (3,372)
Chronic lymphocytic leukaemia (3,085)
Other Drugs Used for Factor viii deficiency
EMICIZUMAB-KXWH (6,532)
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT (4,268)
EFMOROCTOCOG ALFA (832)
--BLOOD-COAGULATION FACTOR VIII FUSION PROTEIN WITH IMMUNOGLOBULIN G1 , ,-BIS WITH IMMUNOGLOBULIN G1 (722)
ANTIHEMOPHILIC FACTOR, PEGYLATED HUMAN SEQUENCE RECOMBINANT (352)
ANTI-INHIBITOR COAGULANT COMPLEX (317)
EMICIZUMAB (315)
DAMOCTOCOG ALFA PEGOL (310)
EFANESOCTOCOG ALFA (292)
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT RESIDUES 743-1636 DELETED (180)