DACTINOMYCIN for Gestational trophoblastic tumour: Side Effects & Safety Data
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There are 360 adverse event reports in the FDA FAERS database where DACTINOMYCIN was used for Gestational trophoblastic tumour.
Most Reported Side Effects for DACTINOMYCIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 391 | 13.7% | 77 | 63 |
| Febrile neutropenia | 226 | 7.9% | 23 | 144 |
| Neutropenia | 205 | 7.2% | 18 | 67 |
| Product use in unapproved indication | 203 | 7.1% | 45 | 17 |
| Drug ineffective | 181 | 6.3% | 59 | 43 |
| Disease progression | 151 | 5.3% | 59 | 10 |
| Vomiting | 119 | 4.2% | 20 | 54 |
| Anaemia | 109 | 3.8% | 5 | 46 |
| Thrombocytopenia | 106 | 3.7% | 5 | 47 |
| Malignant neoplasm progression | 103 | 3.6% | 50 | 3 |
| Stomatitis | 103 | 3.6% | 1 | 57 |
| Maternal exposure before pregnancy | 99 | 3.5% | 1 | 0 |
| Acute myeloid leukaemia | 98 | 3.4% | 63 | 6 |
| Ovarian failure | 92 | 3.2% | 0 | 1 |
| Drug resistance | 87 | 3.0% | 24 | 12 |
Other Indications for DACTINOMYCIN
Ewing's sarcoma (282)
Nephroblastoma (278)
Embryonal rhabdomyosarcoma (271)
Rhabdomyosarcoma (220)
Choriocarcinoma (210)
Alveolar rhabdomyosarcoma (134)
Product used for unknown indication (95)
Chemotherapy (89)
Atypical teratoid/rhabdoid tumour of cns (61)
Metastases to lung (57)
Other Drugs Used for Gestational trophoblastic tumour
METHOTREXATE (488)
ETOPOSIDE (419)
CYCLOPHOSPHAMIDE (255)
VINCRISTINE (242)
CISPLATIN (179)
CARBOPLATIN (63)
LEUCOVORIN (58)
PACLITAXEL (55)
BLEOMYCIN (38)
PEMBROLIZUMAB (27)