DARATUMUMAB for Plasma cell leukaemia: Side Effects & Safety Data
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There are 192 adverse event reports in the FDA FAERS database where DARATUMUMAB was used for Plasma cell leukaemia.
Most Reported Side Effects for DARATUMUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Plasma cell myeloma | 2,980 | 10.9% | 680 | 439 |
| Infusion related reaction | 2,557 | 9.3% | 241 | 629 |
| Off label use | 2,494 | 9.1% | 425 | 783 |
| Pneumonia | 1,450 | 5.3% | 336 | 1,018 |
| Neutropenia | 1,351 | 4.9% | 192 | 371 |
| Drug ineffective | 1,110 | 4.1% | 240 | 217 |
| Thrombocytopenia | 1,089 | 4.0% | 199 | 374 |
| Death | 1,088 | 4.0% | 1,088 | 200 |
| Pyrexia | 1,032 | 3.8% | 140 | 592 |
| Dyspnoea | 996 | 3.6% | 98 | 404 |
| Neuropathy peripheral | 955 | 3.5% | 45 | 116 |
| Anaemia | 925 | 3.4% | 171 | 380 |
| Diarrhoea | 916 | 3.3% | 130 | 414 |
| Fatigue | 796 | 2.9% | 73 | 207 |
| Intentional product use issue | 711 | 2.6% | 56 | 108 |
Other Indications for DARATUMUMAB
Plasma cell myeloma (19,119)
Product used for unknown indication (4,960)
Plasma cell myeloma refractory (789)
Primary amyloidosis (609)
Amyloidosis (417)
Plasma cell myeloma recurrent (131)
Plasmablastic lymphoma (79)
Plasmacytoma (79)
Nephrotic syndrome (63)
Poems syndrome (62)
Other Drugs Used for Plasma cell leukaemia
LENALIDOMIDE (797)
DEXAMETHASONE (512)
BORTEZOMIB (458)
CYCLOPHOSPHAMIDE (256)
POMALIDOMIDE (209)
DOXORUBICIN (199)
CARFILZOMIB (186)
ETOPOSIDE (116)
CISPLATIN (99)
THALIDOMIDE (94)