Does DARATUMUMAB Cause Bradycardia? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Bradycardia have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.3% of all adverse event reports for DARATUMUMAB.
85
Reports of Bradycardia with DARATUMUMAB
0.3%
of all DARATUMUMAB reports
6
Deaths
35
Hospitalizations
How Dangerous Is Bradycardia From DARATUMUMAB?
Of the 85 reports, 6 (7.1%) resulted in death, 35 (41.2%) required hospitalization, and 7 (8.2%) were considered life-threatening.
Is Bradycardia Listed in the Official Label?
Yes, Bradycardia is listed as a known adverse reaction in the official FDA drug label for DARATUMUMAB.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Bradycardia?
BISOPROLOL (2,535)
METOPROLOL (2,024)
AMLODIPINE (1,840)
AMIODARONE (1,261)
FUROSEMIDE (1,032)
ATENOLOL (942)
PROPRANOLOL (934)
DIGOXIN (896)
CARVEDILOL (861)
FINGOLIMOD (861)
Which DARATUMUMAB Alternatives Have Lower Bradycardia Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE