Does DARATUMUMAB Cause Hyperkalaemia? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Hyperkalaemia have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.1% of all adverse event reports for DARATUMUMAB.
34
Reports of Hyperkalaemia with DARATUMUMAB
0.1%
of all DARATUMUMAB reports
10
Deaths
23
Hospitalizations
How Dangerous Is Hyperkalaemia From DARATUMUMAB?
Of the 34 reports, 10 (29.4%) resulted in death, 23 (67.6%) required hospitalization, and 7 (20.6%) were considered life-threatening.
Is Hyperkalaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Hyperkalaemia?
METFORMIN (2,565)
SPIRONOLACTONE (2,518)
FUROSEMIDE (2,035)
RAMIPRIL (1,383)
SACUBITRIL\VALSARTAN (1,192)
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036)
LISINOPRIL (948)
POTASSIUM (944)
BISOPROLOL (850)
TACROLIMUS (713)
Which DARATUMUMAB Alternatives Have Lower Hyperkalaemia Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE