Does DARATUMUMAB Cause Leukopenia? 361 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 361 reports of Leukopenia have been filed in association with DARATUMUMAB (DARZALEX). This represents 1.3% of all adverse event reports for DARATUMUMAB.
361
Reports of Leukopenia with DARATUMUMAB
1.3%
of all DARATUMUMAB reports
41
Deaths
108
Hospitalizations
How Dangerous Is Leukopenia From DARATUMUMAB?
Of the 361 reports, 41 (11.4%) resulted in death, 108 (29.9%) required hospitalization, and 22 (6.1%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 361 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which DARATUMUMAB Alternatives Have Lower Leukopenia Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE