DEFERASIROX for Chelation therapy: Side Effects & Safety Data
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There are 136 adverse event reports in the FDA FAERS database where DEFERASIROX was used for Chelation therapy.
Most Reported Side Effects for DEFERASIROX
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 1,583 | 14.0% | 1,569 | 158 |
| Diarrhoea | 993 | 8.8% | 85 | 352 |
| Serum ferritin increased | 732 | 6.5% | 112 | 318 |
| Haemoglobin decreased | 615 | 5.4% | 109 | 385 |
| Pyrexia | 607 | 5.4% | 122 | 465 |
| Malaise | 605 | 5.3% | 99 | 323 |
| Nausea | 603 | 5.3% | 62 | 247 |
| Sickle cell anaemia with crisis | 570 | 5.0% | 11 | 479 |
| Vomiting | 520 | 4.6% | 52 | 300 |
| Pneumonia | 494 | 4.4% | 152 | 384 |
| Fatigue | 438 | 3.9% | 67 | 216 |
| Abdominal pain | 433 | 3.8% | 22 | 223 |
| Pain | 380 | 3.4% | 39 | 278 |
| Platelet count decreased | 353 | 3.1% | 111 | 190 |
| Abdominal pain upper | 345 | 3.1% | 29 | 144 |
Other Indications for DEFERASIROX
Iron overload (2,712)
Product used for unknown indication (2,372)
Myelodysplastic syndrome (1,445)
Sickle cell anaemia (883)
Thalassaemia (560)
Haemochromatosis (502)
Thalassaemia beta (385)
Sickle cell disease (306)
Aplastic anaemia (277)
Iron metabolism disorder (195)